Thermo Fisher Scientific Human PARP1 His-tag Recombinant Protein
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Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
Immunohistochemistry (IHC)
Assay-dependent
ELISA (ELISA)
Assay-dependent
Functional Assay (Functional)
Assay-dependent
Control (Ctrl)
Assay-dependent
Product Specifications
Expression System
Insect cells
Class
Recombinant
Type
Protein
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient
Target Information
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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