Thermo Fisher Scientific CYP11B2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human CYP11B2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2609272

Product Specific Information

Peptide sequence: RRLAEAEMLL LLHHVLKHFL VETLTQEDIK MVYSFILRPG TSPLLTFRAI

Sequence homology: Horse: 79%; Human: 100%

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.