Thermo Scientific™

Mass Spectrometry Compatible Crosslinkers

Improve mass spectrometry detection of crosslinked proteins and interactions with DSPP and TBDSPP heterotrifunctional crosslinkers.

Chemical crosslinking in combination with mass spectrometry is a powerful method to improve protein characterization, and to identify protein-protein interactions. This method has been applied to recombinant and native protein complexes, and more recently, to whole cell lysates or intact unicellular organisms in efforts to identify protein-protein interactions on a global scale. The enrichment feature of DSPP and TBDSPP improves detection of crosslinked proteins by reducing sample complexity through separation of crosslinked from non-crosslinked peptides.

사양

화학물질 반응성Amine-Amine

CleavableNo

설명DSPP

분자량440.25

페길레이티드No

순도90%

스페이서 암 길이4.3 Å

세포 투과성No

제품라인MS Reagents

라벨링 방법Chemical Labeling

교차결합제 유형Homotrifunctional

반응성 부분NHS Ester

스페이서Medium (10 to 30 Å)

형태Solid

수량50 mg

용해도Water

형식Standard

수용성Yes

제품 유형Crosslinker

Unit SizeEach