Thermo Fisher Scientific OGDH Monoclonal Antibody (9F4BD5)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.25 µg/mL

-

Immunocytochemistry (ICC/IF)

1.0 µg/mL

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

9F4BD5

Immunogen

Purified OGDH from porcine heart, purified GLUD from bovine liver.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C

RRID

AB_2535906

Target Information

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.