Thermo Scientific™

Tango™ HTR1A-bla U2OS Cells

Tango™ HTR1A-bla U2OS cells contain the human Serotonin Type 1a receptor (HTR1A) linked to a TEV protease site and a자세히 알아보기

Tango™ HTR1A-bla U2OS cells contain the human Serotonin Type 1a receptor (HTR1A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. Tango™ HTR1A-bla U2OS DA cells have been functionally validated for Z` factor and EC50 concentrations of 5-CT (Figure 1). In addition, Tango™ HTR1A-bla U2OS cells have been tested for assay performance under variable conditions.

사양

등록 번호NM_000524

어세이 입력Cell-based beta-arrestin recruitment

셀 상태Dividing Cells

세포질 후미Tail from AVPR2 GPCR

검출 방법Fluorescence

용도(애플리케이션)FRET

유전자 기호HTR1A

인간 단백질 분류G-Protein Coupled Receptor (GPCR)

개체군 상태Single Cell Clone Origin

제품라인Tango™

수량8 x 106 Cells

판독End Point

타겟 입력5HT1A, HTR1A

세포주U2OS

System TypeTango™

Druggable TargetGPCR

Unit SizeEach